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Cecilia Brown
Articles by Cecilia Brown
HARMONi-2 Interim Analysis: Ivonescimab Shows PFS Improvements Over Pembrolizumab in NSCLC
Cecilia Brown
Immunotherapy in NSCLC
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March 7, 2025
The study investigators concluded that ivonescimab “might represent another treatment option in the first-line setting."
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Stephen Liu, MD, on Key Debates in NSCLC
Stephen V. Liu, MD
Non-Small Cell Lung Cancer
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March 7, 2025
Dr. Liu unpacks key questions in the field, and the research that could address them.
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How Frequent Is Suture-Line Recurrence After Surgery for Early-Stage NSCLC?
Cecilia Brown
Non-Small Cell Lung Cancer
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March 5, 2025
Certain surgical procedures and margins were more frequent in patients who had suture-line recurrences.
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CROWN 5-Year Subgroup Analysis Shows PFS Is Consistent With Overall Patient Population
Cecilia Brown
ALK+ NSCLC
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March 5, 2025
The long-term follow-up data shows that PFS remains unreached in the subgroup of Asian patients in the CROWN study.
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Can Systematic Immune Inflammation Predict Survival in Patients Receiving Immune Checkpoint Inhibitors for NSCLC?
Cecilia Brown
Immunotherapy in NSCLC
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March 5, 2025
Researchers evaluated if there was a link between pretreatment systemic immune inflammation index levels and outcomes.
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LUPER Study Evaluates Lurbinectedin Plus Pembrolizumab in Relapsed SCLC
Cecilia Brown
Small Cell Lung Cancer
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March 5, 2025
Study investigators say the combination "showed promising efficacy" in patients with relapsed small cell lung cancer.
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Study Sheds Light on Real-World Outcomes With Different KRAS Mutations in NSCLC
Cecilia Brown
KRAS+ NSCLC
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February 26, 2025
Researchers evaluated if demographics, clinical characteristics, and outcomes varied between those with KRAS G12C and G12D.
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FDA Grants Fast Track Designation to IBI363 for Squamous NSCLC
Cecilia Brown
Immunotherapy in NSCLC
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February 25, 2025
The therapy is currently under evaluation in phase 1 and phase 2 trials.
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Dr. Nieva Shares Insights From Epidemiology of Young Lung Cancer Trial
Jorge Nieva, MD
WCLC 2024
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February 24, 2025
A distributed clinical trial is analyzing diet and exercise patterns in young people with lung cancer.
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FDA Grants Priority Review to Zongertinib for HER2-Mutated NSCLC
Cecilia Brown
Non-Small Cell Lung Cancer
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February 21, 2025
The Prescription Drug User Fee Act action date is expected in the third quarter of 2025.
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Stephen Liu, MD, Shares Insights on the eNRGy Trial
Stephen V. Liu, MD
Non-Small Cell Lung Cancer
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February 20, 2025
Dr. Liu unpacks the trial results, the recent approval, and the unique biomarker testing considerations for NRG1 fusions.
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CheckMate-816 Shows Significant Improvement in OS With Neoadjuvant Nivolumab Plus Chemotherapy for Resectable NSCLC
Cecilia Brown
Immunotherapy in NSCLC
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February 19, 2025
It is the "first and only neoadjuvant-only immuno-oncology therapy" to show a significant OS benefit in this setting.
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The STS General Thoracic Surgery Database: Task Force Chair Shares Insights, Updates
Christopher Seder, MD
STS 2025
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February 14, 2025
Christopher Seder, MD, discusses the database and how it can be used for research, quality improvement, and risk ...
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ALK Positive Announces Formation of Scientific Advisory Board
Ken Culver, MD
ALK+ NSCLC
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February 13, 2025
The 12-member board will guide the guide the patient-driven organization’s research and strategic priorities.
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Phase 3 HARMONi-6/AK112-306 Trial of Ivonescimab Plus Chemotherapy for NSCLC Completes Enrollment
Cecilia Brown
Immunotherapy in NSCLC
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February 12, 2025
The study is comparing ivonescimab plus platinum-based chemotherapy with tislelizumab plus platinum-based chemotherapy.
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The Future of Surgery for Stage IV Lung Cancer: Dr. Antonoff Shares Hopes, Insights
Mara B. Antonoff, MD, FACS
STS 2025
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February 11, 2025
Mara B. Antonoff, MD, FACS, discusses what could be on the horizon for surgery in stage IV lung cancer.
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Phase 2 eNRGy Trial: Zenocutuzumab Shows Efficacy in NRG1 Fusion–Positive NSCLC
Cecilia Brown
Non-Small Cell Lung Cancer
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February 10, 2025
The bispecific antibody, which recently received FDA accelerated approval, showed a response rate of 29% in NSCLC.
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EMA CHMP Recommends Durvalumab for Limited-Stage SCLC
Cecilia Brown
Small Cell Lung Cancer
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February 6, 2025
The recommendation is based on results from the phase 3 ADRIATIC trial.
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Phase 3 ResQ201A-NSCLC Trial to Evaluate Nogapendekin Alfa Inbakicept Plus Tislelizumab
Cecilia Brown
Immunotherapy in NSCLC
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February 5, 2025
The study aims to confirm safety and efficacy findings from the phase 2 QUILT 3.055 trial.
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Stephen Liu, MD, Discusses the COCOON Study
Stephen V. Liu, MD
EGFR+ NSCLC
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February 4, 2025
The study is evaluating a prophylactic dermatologic regimen in patients receiving amivantamab plus lazertinib.
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